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Inhalers Day Supply Calculations (MDI, DPI, Nebulizer Solution)

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Inhalers and Day Supply Calculation

Calculating the day supply of an inhaler is essential for proper medication management, insurance billing, and ensuring patients have enough medication.

The day supply depends on the total number of doses in the inhaler and the prescribed dosage (how many puffs per day).

1. Know the Inhaler Type

  • Metered Dose Inhalers (MDIs): Deliver a fixed number of puffs (e.g., 120 actuations).
  • Dry Powder Inhalers (DPIs): Also contain a set number of doses (e.g., 60 blister packs).
  • Respimat inhalers: Contain a set number of actuations (e.g., 120 sprays).
  • Nebulizer solutions: Measured in mL or unit doses, not “puffs”.

2. Find the Total Number of Doses

Look at the packaging or drug database. It will say something like:
  • 200 inhalations
  • 60 doses
  • 120 metered sprays
Example: Albuterol Inhaler (ProAir HFA) = 200 inhalations

3. Confirm Prescribed Usage

Check the prescription for dosing frequency, such as:
  • 2 puffs every 4 to 6 hours PRN
  • 1 puff twice daily
  • 2 puffs QID

4. Calculate Day Supply

Inhalers and Day Supply Calculation Formula Inhalers Day Supply Calculation Formula

Inhalers Day Supply Calculations

What are Metered Dose Inhalers (MDIs)?

Metered Dose Inhalers (MDIs) are handheld devices that deliver a specific amount of medication in aerosol form directly into the lungs. They use a propellant to release the drug when the canister is pressed.

MDIs are commonly used to treat asthma, COPD, and other respiratory conditions. Proper technique, including slow, deep inhalation and coordination between actuation and breathing, is essential for effective drug delivery.

Spacers are often recommended to improve medication deposition and reduce side effects like oral thrush when using corticosteroids.

Common Metered Dose Inhalers (MDI)

Brand NameGeneric NameTotal Puffs
ProAir HFAAlbuterol200
Proventil HFAAlbuterol200
Ventolin HFAAlbuterol200
AirsupraAlbuterol / Budesonide120
QVAR RediHalerBeclomethasone120
BreynaBudesonide / Formoterol120
SymbicortBudesonide / Formoterol120
AlvescoCiclesonide60
Flovent HFAFluticasone propionate120
Advair HFAFluticasone / Salmeterol120
Bevespi AerosphereGlycopyrrolate / Formoterol120
Atrovent HFAIpratropium200
Combivent RespimatIpratropium / Albuterol120
Xopenex HFALevalbuterol200
Asmanex HFAMometasone100
DuleraMometasone / Formoterol120
Spiriva RespimatTiotropium60
Stiolto RespimatTiotropium / Olodaterol60

What are Dry Powder Inhalers (DPIs)?

Dry Powder Inhalers (DPIs) are handheld devices that deliver medication in the form of a dry powder directly to the lungs. Unlike metered-dose inhalers (MDIs), DPIs are breath-actuated, meaning the patient’s inhalation provides the force to disperse and inhale the medication—no propellant is used.

DPIs are commonly used for asthma and COPD treatments. Proper inhalation technique is crucial: a quick, deep breath ensures effective drug delivery. DPIs come in various designs like Diskus, Ellipta, and HandiHaler, each with unique loading and usage methods. They are ideal for patients who may struggle with MDI coordination.

Common Dry Powder Inhalers (DPI)

Brand Name Generic Name Total Doses
ProAir Digihaler Albuterol 200
Pulmicort Flexhaler Budesonide 60 / 120
Arnuity Ellipta Fluticasone furoate 30
ArmonAir Digihaler Fluticasone propionate 60
Flovent Diskus Fluticasone propionate 60
Advair Diskus Fluticasone / Salmeterol 60
AirDuo RespiClick Fluticasone / Salmeterol 60
Wixela Inhub Fluticasone / Salmeterol 60
AirDuo Digihaler Fluticasone / Salmeterol 60
Trelegy Ellipta Fluticasone / Umeclidinium / Vilanterol 30
Breo Ellipta Fluticasone / Vilanterol 30
Seebri Neohaler Glycopyrrolate 30
Arcapta Neohaler Indacaterol 30
Utibron Neohaler Indacaterol / Glycopyrrolate 30
Asmanex Twisthaler Mometasone 30 / 60 / 120
Serevent Diskus Salmeterol 60
Spiriva HandiHaler Tiotropium 30
Incruse Ellipta Umeclidinium 30
Anoro Ellipta Umeclidinium / Vilanterol 30
Dry Powder Inhaler (DPI)

What are Respimat Inhalers?

Respimat inhalers are a type of Soft Mist Inhaler (SMI) that deliver medication as a slow-moving mist, providing better drug deposition in the lungs compared to traditional metered-dose inhalers (MDIs).

Unlike MDIs, Respimats do not require a propellant and are breath-actuated. They are primarily used for conditions like asthma and COPD, delivering medications such as LAMA, LABA, or a combination. Due to their gentle mist, Respimats are often preferred for patients with difficulty coordinating an MDI. Popular brands include Spiriva Respimat, Combivent Respimat, and Stiolto Respimat.

Common Respimat Inhalers

Brand NameGeneric NameTotal Puffs
Combivent RespimatIpratropium / Albuterol120
Striverdi RespimatOlodaterol60
Spiriva RespimatTiotropium60
Spiriva Respimat (asthma)Tiotropium60
Stiolto RespimatTiotropium / Olodaterol60

What are Nebulizer Solutions/Vials?

Nebulizer solutions/vials are liquid medications used in nebulizers to treat respiratory conditions like asthma and COPD. They deliver the medication as a fine mist that patients inhale through a mask or mouthpiece.

These solutions can include bronchodilators, corticosteroids, or antibiotics and are typically dosed multiple times daily.

Common Nebulizer Solutions/Vials

Brand Name Generic Name Size of Each Vial
Albuterol Sulfate Albuterol 2.5 mg/3 mL
Proventil Nebulizer Albuterol 2.5 mg/3 mL
Ventolin Nebulizer Albuterol 2.5 mg/3 mL
Brovana Arformoterol 15 mcg/2 mL
Pulmicort Budesonide 0.25 mg/2 mL, 0.5 mg/2 mL
Perforomist Formoterol Fumarate 20 mcg/2 mL
Arcapta Neohaler Indacaterol 1.75 mg/2 mL
Atrovent Ipratropium Bromide 0.02% (0.5 mg/2.5 mL)
Combivent Respimat Ipratropium / Albuterol 0.5 mg/2.5 mL
Duoneb Ipratropium / Albuterol 0.5 mg/2.5 mL
Xopenex Levalbuterol 0.63 mg/3 mL or 1.25 mg/3 mL
Tobi Tobramycin 300 mg/5 mL

Metered Dose Inhaler (MDI) Practice Questions

Question 1: A patient is prescribed Ventolin HFA (Albuterol) 2 puffs every 4-6 hours as needed. The inhaler contains 200 puffs. What is the maximum day supply?

Explanation:
  • Max puffs per day = 2 puffs × 6 times = 12 puffs/day.
  • Day supply = 200 puffs ÷ 12 puffs/day = 16 days.
The correct answer is 16 days. Ventolin pump should last 16 days)

Question 2: A patient is prescribed Flovent HFA (Fluticasone propionate) 2 puffs twice daily. The inhaler contains 120 puffs. The day supply of this inhaler is __________ days.

Explanation:
  • Max puffs per day: 2 puffs × 2 times/day = 4 puffs/day.
  • Day supply = 120 puffs ÷ 4 puffs/day = 30 days.

Question 3: Xopenex HFA (Levalbuterol) contains 200 puffs. A patient is prescribed 2 puffs every 4-6 hours, with a maximum day supply?

Explanation:
  • Max puffs per day = 2 puffs × 12 doses = 24 puffs/day.
  • Day supply = 200 puffs ÷ 24 puffs/day = 8.33 days.
  • Round to 8 days.

Question 4: A patient is prescribed Alvesco (Ciclesonide) 1 puff daily. The inhaler contains 120 puffs. How many days will the inhaler last?

Explanation:
  • Max puffs per day: 1 puff/day = 1 puff daily.
  • Day supply = 120 puffs ÷ 1 puff/day = 120 days.

Powdered Dose Inhaler (PDI) Practice Questions

Question 5: A patient is prescribed Flovent Diskus (Fluticasone propionate) 250 mcg twice daily (1 puff in the morning and 1 in the evening). The inhaler contains 60 doses. How many days will this inhaler last?

Explanation:
  • Since the prescribed dose is 2 puffs daily (1 puff in the morning and 1 in the evening), and
  • Inhaler contains 60 doses, the
  • Day supply is: 60 doses ÷ 2 puffs/day = 30 days.

Question 6: A patient is prescribed Symbicort (Budesonide/Formoterol) inhaler with 120 doses. If the patient uses 2 puffs twice daily, the inhaler will last for ______ days.

Explanation:
  • The patient is using 4 puffs per day (2 puffs AM, 2 puffs PM). Day supply is: 120 doses ÷ 4 puffs/day = 30 days.

Question 7: An inhaler of Pulmicort Flexhaler (Budesonide) contains 120 doses. The prescription is for 1 puff twice daily. How many days will this inhaler last, and what is the total number of puffs used per month?

Explanation:
  • 1 Puff twice daily = 2 puffs / day
  • Days supply: 120 doses ÷ 2 puffs / day = 60 days Total puffs per month: 2 puffs/day × 30 days = 60 puffs per month

Question 8: A patient is prescribed Arnuity Ellipta (Fluticasone furoate) with 30 doses. The patient is directed to use 1 puff daily. After 10 days of use, the patient reports they have used 5 doses. How many doses remain, and how many days of treatment are left?

Explanation:
  • Doses remaining: 30 doses – 5 doses used = 25 doses remaining
  • Days remaining: 25 doses ÷ 1 puff/day = 25 days remaining
After 10 days, the patient has used 5 doses. Therefore, 25 doses remain, which will last for 25 more days with the prescribed use of 1 puff daily.

Respimat Inhaler Practice Questions

Question 9: A patient is prescribed Spiriva Respimat for asthma with the following directions: “2 puffs once daily.” The Spiriva Respimat inhaler contains 60 puffs. What is the day supply of this inhaler?

Explanation:
  • Total puffs: Each Spiriva Respimat inhaler has 60 puffs.
  • Dose prescribed: 2 puffs once daily
  • Total day supply: 60 puffs ÷ 2 puffs/day = 30 days.

Question 10: A patient is prescribed Combivent Respimat with the following directions: “1 puff QID” (four times a day). The inhaler contains 120 puffs. If the patient forgets to take a dose for 2 days, how many days will the inhaler last?

Explanation: This question has 2 parts
  • Part 1: The patient typically uses 1 puff four times a day, so the inhaler would (120 puffs ÷ 4 puffs/day) = last 30 days.
  • Part 2: If they miss 2 days, they still have 2 extra days left from the missed doses. Therefore, the inhaler will last 32 days.

Nebulizer Solutions/Vials Practice Questions

Question 11: A patient is prescribed Albuterol 2.5 mg/3 mL nebulizer solution to be used QID (4 times a day). The package size is 90 mL. How many days will the package last?

Explanation:
  • Determine the volume used per day:
    • The prescribed dose is 3 mL QID (4 times a day).
    • So, the patient uses 3 mL × 4 doses = 12 mL/day.
  • Calculate the day supply:
    • The total volume in the package is 90 mL.
    • To calculate how many days the package will last:
Day Supply Calculation Formula for Nebulizer

Answer: The package will last 7.5 days.

Question 12: A patient is prescribed Budesonide (Pulmicort) 0.5 mg/2 mL nebulizer suspension to be used BID (twice daily). The package contains 30 vials, each with 2 mL. How many days will the package last?

Explanation:
  • Determine how many vials are used per day:
    • The dose is 1 vial (2 mL) BID.
    • So, the patient uses 2 vials per day.
  • Calculate the day supply:
    • The package contains 30 vials.
Day Supply Calculation Formula for Budesonide Nebulizer

Answer: The package will last 15 days.