The Pharmacy Technician Certification Exam (PTCE), administered by the Pharmacy Technician Certification Board (PTCB), is a comprehensive test designed to assess the knowledge and skills required for entry-level pharmacy technicians. Here’s a breakdown of PTCB exam:

 PTCB Exam Format

  • Total Questions: 90 questions (80 scored + 10 unscored pilot questions).
  • Time Limit: 1 hour and 50 minutes (110 minutes).
  • Question Type: Multiple-choice questions (MCQs) with four answer options.
  • Passing Score: Scaled score of 1,400 (on a scale of 1,000 to 1,600).

PTCB Exam Content

The PTCE is divided into four knowledge domains, each with a specific weighting:
  1. Medications (40%):

    • Focuses on drug names (generic and brand), classifications, therapeutic uses, side effects, and interactions.
    • Includes high-alert medications and look-alike/sound-alike (LASA) drugs.
  2. Federal Requirements (12.5%):

    • Covers federal laws and regulations, such as the Controlled Substances Act (CSA), HIPAA, and FDA regulations.
    • Tests knowledge of DEA requirements and drug scheduling.
  3. Patient Safety and Quality Assurance (26.25%):

    • Emphasizes medication safety, error prevention, and quality assurance.
    • Includes pharmacy calculations, compounding, and hazardous drug handling.
  4. Order Entry and Processing (21.25%):

    • Focuses on prescription processing, insurance billing, inventory management, and pharmacy technology.
    • Tests communication skills and customer service.

Key Points

  • Computer-Based Testing: The exam is administered at Pearson VUE testing centers.
  • Unscored Questions: 10 pilot questions are included for future exam development and do not affect your score.
  • Immediate Results: Candidates receive a preliminary pass/fail result at the testing center.
  • Official Score Report: A detailed score report is available online within 2-3 weeks.

PTCB Preparation Tips

  1. Study the PTCB Blueprint: Focus on the four domains and their weightings.
  2. Practice Calculations: Pharmacy math is a significant part of the exam.
  3. Memorize Drug Names: Learn generic and brand names, especially the Top 200 drugs.
  4. Understand Laws and Regulations: Review federal requirements and patient safety guidelines.

PTCB Blueprint

  • Medications
    (40% of PTCE​ Exam Content)

  • S. No.

    Knowledge Domains and Areas

    Flashcards

    Questions

  • 1.1

    Generic names, brand names, and classifications
    of medications

    Yes

    Yes

  • 1.2

    Therapeutic equivalence

    Yes

    Yes

  • 1.3

    Common and life-threatening drug interactions and contraindications (e.g., drug-disease, drug-drug, drug-dietary supplement, drug-laboratory, drug-nutrient)

    Yes

    Yes

  • 1.4

    Strengths/dose, dosage forms, routes of administration, special handling and
    administration instructions, and duration of
    drug therapy

    Yes

    Yes

  • 1.5

    Common and severe medication side effects, adverse effects, and allergies

    Yes

    Yes

  • 1.6

    Indications of medications and
    dietary supplements

    Yes

    Yes

  • 1.7

    Drug stability (e.g., oral suspensions, insulin, reconstitutables, injectables, vaccinations)

    Yes

    Yes

  • 1.8

    Narrow therapeutic index (NTI) medications

    Yes

    Yes

  • 1.9

    Physical and chemical incompatibilities
    related to non-sterile compounding and reconstitution

    Yes

    Yes

  • 1.10

    Proper storage of medications
    (e.g., temperature ranges, light sensitivity, restricted access)

    Yes

    Yes

  • Federal Requirements
    (12.5% of PTCE​ Exam Content)

  • S. No.

    Knowledge Domains and Areas

    Flashcards

    Questions

  • 2.1

    Federal requirements for handling and
    disposal of non-hazardous, hazardous,
    and pharmaceutical substances and waste

    Yes

    Yes

  • 2.2

    Federal requirements for controlled substance prescriptions (i.e., new, refill, transfer) and
    DEA controlled substance schedules

    Yes

    Yes

  • 2.3

    Federal requirements (e.g., DEA, FDA) for controlled substances (i.e., receiving, storing, ordering, labeling, dispensing, reverse
    distribution, take-back programs, and loss
    or theft of)

    Yes

    Yes

  • 2.4

    Federal requirements for restricted drug
    programs and related medication processing
    (e.g., pseudoephedrine, Risk Evaluation and Mitigation Strategies [REMS])

    Yes

    Yes

  • 2.5

    FDA recall requirements (e.g., medications,
    devices, supplies, supplements, classifications)

    Yes

    Yes

  • Patient Safety and Quality Assurance
    (26.25% of PTCE​ Exam Content)

  • S. No.

    Knowledge Domains and Areas

    Flashcards

    Questions

  • 3.1

    High-alert/risk medications and
    look-alike/sound-alike [LASA] medications

    Yes

    Yes

  • 3.2

    Error prevention strategies (e.g., prescription
    or medication order to correct patient,
    Tall Man lettering, separating inventory, leading and trailing zeros, bar code usage, limit use of
    error-prone abbreviations)

    Yes

    Yes

  • 3.3

    Issues that require pharmacist intervention
    (e.g., drug utilization review [DUR], adverse
    drug event [ADE], OTC recommendation, therapeutic substitution, misuse, adherence,
    post-immunization follow-up, allergies, drug interactions)

    Yes

    Yes

  • 3.4

    Event reporting procedures (e.g., medication errors, adverse effects, and product integrity, MedWatch, near miss, root-cause analysis
    [RCA])

    Yes

    Yes

  • 3.5

    Types of prescription errors (e.g., abnormal
    doses, early refill, incorrect quantity, incorrect patient, incorrect drug)

    Yes

    Yes

  • 3.6

    Hygiene and cleaning standards (e.g., handwashing, personal protective equipment [PPE], cleaning counting trays, countertop, and equipment)

    Yes

    Yes

  • Order Entry and Processing
    (21.25% of PTCE​ Exam Content)

  • S. No.

    Knowledge Domains and Areas

    Flashcards

    Questions

  • 4.1

    Procedures to compound non-sterile products
    (e.g., ointments, mixtures, liquids, emulsions, suppositories, enemas)

    Yes

    Yes

  • 4.2

    Formulas, calculations, ratios, proportions, alligations, conversions, Sig codes
    (e.g., b.i.d., t.i.d., Roman numerals),
    abbreviations, medical terminology, and
    symbols for days supply, quantity, dose, concentration, dilutions

    Yes

    Yes

  • 4.3

    Equipment/supplies required for drug administration (e.g., package size, unit dose, diabetic supplies, spacers, oral and injectable syringes)

    Yes

    Yes

  • 4.4

    Lot numbers, expiration dates, and
    National Drug Code (NDC) numbers

    Yes

    Yes

  • 4.5

    Procedures for identifying and returning dispensable, non-dispensable, and expired medications and supplies (e.g., credit return,
    return to stock, reverse distribution)

    Yes

    Yes